• Britton DJ, Hutcheson IR, Knowlden JM, Barrow D, Giles M, McClelland RA, Gee JM, Nicholson RI. Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. Breast Cancer Res Treat. 2006 Mar;96(2):131-46. doi: 10.1007/s10549-005-9070-2. Epub 2005 Oct 27. PMID: 16261397. https://pubmed.ncbi.nlm.nih.gov/16261397/

  • Nicholson RI, Hutcheson IR, Britton D, Knowlden JM, Jones HE, Harper ME, Hiscox SE, Barrow D, Gee JM. Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies. J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):257-62. doi: 10.1016/j.jsbmb.2004.12.006. Epub 2005 Feb 8. PMID: 15860268. https://pubmed.ncbi.nlm.nih.gov/15860268/

     

  • Benz CC, Atsriku C, Yau C, Britton D, Schilling B, Gibson BW, Baldwin MA, Scott GK. Novel pathways associated with quinone-induced stress in breast cancer cells. Drug Metab Rev. 2006;38(4):601-13. doi: 10.1080/03602530600959391. PMID: 17145690. https://pubmed.ncbi.nlm.nih.gov/17145690/

     

  • Britton DJ, Scott GK, Schilling B, Atsriku C, Held JM, Gibson BW, Benz CC, Baldwin MA. A novel serine phosphorylation site detected in the N-terminal domain of estrogen receptor isolated from human breast cancer cells. J Am Soc Mass Spectrom. 2008 May;19(5):729-40. doi: 10.1016/j.jasms.2008.02.008. Epub 2008 Mar 4. PMID: 18367407; PMCID: PMC7456516. https://pubmed.ncbi.nlm.nih.gov/18367407/

     

  • Atsriku C, Britton DJ, Held JM, Schilling B, Scott GK, Gibson BW, Benz CC, Baldwin MA. Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites. Mol Cell Proteomics. 2009 Mar;8(3):467-80. doi: 10.1074/mcp.M800282-MCP200. Epub 2008 Nov 3. PMID: 18984578; PMCID: PMC2649810. https://pubmed.ncbi.nlm.nih.gov/18984578/

     

  • Held JM, Danielson SR, Behring JB, Atsriku C, Britton DJ, Puckett RL, Schilling B, Campisi J, Benz CC, Gibson BW. Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry approach. Mol Cell Proteomics. 2010 Jul;9(7):1400-10. doi: 10.1074/mcp.M900643-MCP200. Epub 2010 Mar 16. PMID: 20233844; PMCID: PMC2938085.https://pubmed.ncbi.nlm.nih.gov/20233844/

     

  • Held JM, Britton DJ, Scott GK, Lee EL, Schilling B, Baldwin MA, Gibson BW, Benz CC. Ligand binding promotes CDK-dependent phosphorylation of ER-alpha on hinge serine 294 but inhibits ligand-independent phosphorylation of serine 305. Mol Cancer Res. 2012 Aug;10(8):1120-32. doi: 10.1158/1541-7786.MCR-12-0099. Epub 2012 Jun 5. PMID: 22669764; PMCID: PMC3950940. https://pubmed.ncbi.nlm.nih.gov/22669764/

     

  • Britton D, Zen Y, Quaglia A, Selzer S, Mitra V, Löβner C, Jung S, Böhm G, Schmid P, Prefot P, Hoehle C, Koncarevic S, Gee J, Nicholson R, Ward M, Castellano L, Stebbing J, Zucht HD, Sarker D, Heaton N, Pike I. Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets. PLoS One. 2014 Mar 26;9(3):e90948. doi: 10.1371/journal.pone.0090948. Erratum in: PLoS One. 2014;9(8):e107077. PMID: 24670416; PMCID: PMC3966770. https://pubmed.ncbi.nlm.nih.gov/24670416/

     

  • Zen Y, Britton D, Mitra V, Pike I, Sarker D, Itoh T, Heaton N, Quaglia A. Tubulin β-III: a novel immunohistochemical marker for intrahepatic peripheral cholangiocarcinoma. Histopathology. 2014 Dec;65(6):784-92. doi: 10.1111/his.12497. Epub 2014 Aug 5. PMID: 25039376. https://pubmed.ncbi.nlm.nih.gov/25039376/

     

  • Böhm G, Prefot P, Jung S, Selzer S, Mitra V, Britton D, Kuhn K, Pike I, Thompson AH. Low-pH Solid-Phase Amino Labeling of Complex Peptide Digests with TMTs Improves Peptide Identification Rates for Multiplexed Global Phosphopeptide Analysis. J Proteome Res. 2015 Jun 5;14(6):2500-10. doi: 10.1021/acs.jproteome.5b00072. Epub 2015 May 13. PMID: 25939058. https://pubmed.ncbi.nlm.nih.gov/25939058/

     

  • Zen Y, Britton D, Mitra V, Pike I, Heaton N, Quaglia A. A global proteomic study identifies distinct pathological features of IgG4-related and primary sclerosing cholangitis. Histopathology. 2016 May;68(6):796-809. doi: 10.1111/his.12813. Epub 2015 Nov 2. PMID: 26308372. https://pubmed.ncbi.nlm.nih.gov/26308372/

     

  • Casado P, Hijazi M, Britton D, Cutillas PR. Impact of phosphoproteomics in the translation of kinase-targeted therapies. Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600235. Epub 2016 Dec 23. PMID: 27774731.https://pubmed.ncbi.nlm.nih.gov/27774731/

     

  • Chen Y, Britton D, Wood ER, Brantley S, Magliocco A, Pike I, Koomen JM. Quantitative proteomics of breast tumors: Tissue quality assessment to clinical biomarkers. Proteomics. 2017 Mar;17(6):10.1002/pmic.201600335. doi: 10.1002/pmic.201600335. PMID: 28127872; PMCID: PMC5996774. https://pubmed.ncbi.nlm.nih.gov/28127872/

     

  • Chen Y, Britton D, Wood ER, Brantley S, Fournier M, Wloch M, Williams VL, Johnson J, Magliocco A, Pike I, Koomen JM. Quantification of Breast Cancer Protein Biomarkers at Different Expression Levels in Human Tumors. Methods Mol Biol. 2018;1788:251-268. doi: 10.1007/7651_2017_113. PMID: 29243084; PMCID: PMC7771335. https://pubmed.ncbi.nlm.nih.gov/29243084/

     

  • Edelmann J, Dokal AD, Vilventhraraja E, Holzmann K, Britton D, Klymenko T, Döhner H, Cragg M, Braun A, Cutillas P, Gribben JG. Rituximab and obinutuzumab differentially hijack the B cell receptor and NOTCH1 signaling pathways. iScience. 2021 Jan 22;24(2):102089. doi: 10.1016/j.isci.2021.102089. PMID: 33615197; PMCID: PMC7878992. https://pubmed.ncbi.nlm.nih.gov/33615197/

     

  • Gerdes H, Casado P, Dokal A, Hijazi M, Akhtar N, Osuntola R, Rajeeve V, Fitzgibbon J, Travers J, Britton D, Khorsandi S, Cutillas PR. Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs. Nat Commun. 2021 Mar 25;12(1):1850. doi: 10.1038/s41467-021-22170-8. PMID: 33767176; PMCID: PMC7994645. https://pubmed.ncbi.nlm.nih.gov/33767176/

     

  • Khorsandi SE, Dokal AD, Rajeeve V, Britton DJ, Illingworth MS, Heaton N, Cutillas PR. Computational Analysis of Cholangiocarcinoma Phosphoproteomes Identifies Patient-Specific Drug Targets. Cancer Res. 2021 Nov 15;81(22):5765-5776. doi: 10.1158/0008-5472.CAN-21-0955. Epub 2021 Sep 22. PMID: 34551960; PMCID: PMC9397618. https://pubmed.ncbi.nlm.nih.gov/34551960/

     

  • Borek WE, Nobre L, Pedicona SF, Campbell AE, Christopher JA, Nawaz N, Perkins DN, Moreno-Cardoso P, Kelsall J, Ferguson HR, Patel B, Gallipoli P, Arruda A, Ambinder AJ, Thompson A, Williamson A, Ghiaur G, Minden MD, Gribben JG, Britton DJ, Cutillas PR, Dokal AD. Phosphoproteomics predict response to midostaurin plus chemotherapy in independent cohorts of FLT3-mutated acute myeloid leukaemia. EBioMedicine. 2024 Oct;108:105316. doi: 10.1016/j.ebiom.2024.105316. Epub 2024 Sep 17. PMID: 39293215; PMCID: PMC11424955. https://pubmed.ncbi.nlm.nih.gov/39293215/

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